PRODUCT Properties
Melting point: | 130-131° |
alpha | D15 -43° (alc) |
Boiling point: | 473.76°C (rough estimate) |
Density | 1.0909 (rough estimate) |
refractive index | 1.5614 (estimate) |
pka | 14.34±0.20(Predicted) |
optical activity | -4315 (c1, ethanol) |
Description and Uses
Lobeline is mainly present in Lobelia chinensis, Lobelia inflata, Campanula medium, Lobelia hassleri, and Lobelia nicotianaefolia . Lobelia inflata has also been considered as an Indian tobacco and has been used for the treatment of respiratory diseases for a long history. It was also a treatment of asthma by American Aborigines. In the United States during the nineteenth century, doctors use Lobelia inflata as a vomiting agent, to remove the poison from the body. It is also called “vomit grass.” Now Lobelia inflata is still used to clear throat, bronchial, lung, and other respiratory mucus .
Lobeline is the principal lobelia alkaloid.It occurs in the seeds and herb of Indiantobacco (Lobelia inflata and Lobeliaceae). Itis used as a respiratory stimulant. Its sulfatesalt is used in antismoking tablets.
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301+H311+H331 |
Hazard Codes | T |
Risk Statements | 23/24/25 |
Safety Statements | 36/37/39-45 |
RIDADR | 1544 |
HazardClass | 6.1(b) |
PackingGroup | III |