M3501935
Ligustilide , 98% , 81944-09-4
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB148.80 | In Stock |
|
| 25mg | RMB489.60 | In Stock |
|
| 100mg | RMB1426.40 | In Stock |
|
| 500mg | RMB3958.40 | In Stock |
|
| 1g | RMB5280.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 168 °C |
| Density | 1.10±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | -20°C, protect from light, stored under nitrogen |
| solubility | DMF:1.0(Max Conc. mg/mL);5.26(Max Conc. mM) DMSO:50.5(Max Conc. mg/mL);265.45(Max Conc. mM) |
| form | Liquid |
| color | Colorless to light yellow |
| LogP | 1.710 (est) |
Description and Uses
(Z)-Ligustilide is extracted from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, exhibits an average antifungal score of 5.6[1]. (Z)-Ligustilide is orally active, it inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD) [2]. (Z)-Ligustilide is also able to reactivate ERα, has epigenetic regulation, and is used in the study of tamoxifen-resistant breast cancer[3].
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
