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M3491035

Lincomycin , 98% , 154-21-2

CAS NO.:154-21-2

Empirical Formula: C18H34N2O6S

Molecular Weight: 406.54

MDL number: MFCD00135816

EINECS: 205-824-6

Pack Size Price Stock Quantity
5mg RMB148.80 In Stock
25mg RMB518.40 In Stock
100mg RMB1452.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 148-150°C
Boiling point: 646.8±55.0 °C(Predicted)
Density  1.1704 (rough estimate)
refractive index  1.6510 (estimate)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water
pka 7.6(at 25℃)
form  Solid
color  White to Off-White
Stability: Hygroscopic
NIST Chemistry Reference Lincomycin(154-21-2)
EPA Substance Registry System Lincomycin (154-21-2)

Description and Uses

Lincomycin was isolated from a strain of Streptomyces lincolnensis in the Upjohn Research Laboratories. Lincosamides are also produced by S. roseolus, S. caelestis, and Monomicrospora halophytica. They consist of an amino acid connected to a sugar by an amide bond. It is available for intravenous, intramuscular, oral, and rectal use. Absorption after oral administration is up to one-third of the dose and plasma protein binding is around 75%. Because of the superior activity and bioavailability of clindamycin, lincomycin is now infrequently used clinically, but it is still available in some countries, in particular for skin and skin structure infections. Thus, the information in this chapter will primarily apply to clindamycin. Many chemical modifications of the lincomycin molecule have been developed and, of these, clindamycin (7-chloro-7-deoxylincomycin) is the most promising and clinically superior to lincomycin.

An antibiotic produced by Streptomyces lincolnensis. Antibacterial

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazardous Substances Data 154-21-2(Hazardous Substances Data)
Toxicity LD50 oral in rat: 1gm/kg

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