LY127809 , 99% , 66104-23-2

Synonym(s):
8β-[(Methylthio)methyl]-6-propylergoline methanesulfonate salt;Pergolide mesylate salt;Pergolide methanesulfonate salt

CAS NO.：66104-23-2

Empirical Formula: C20H30N2O3S2

Molecular Weight: 410.59

MDL number: MFCD00153859

PRODUCT Properties

• Melting point: 252-254°C
• alpha: aD20 between -18.0° and -23.0° (c = 10 mg/ml in DMF)
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: ethanol: soluble2mg/mL
• pka: pKa (66% DMF) 7.8(at 25℃)
• form: solid
• color: white
• optical activity: [α]20/D 35°, c = 0.2 in pyridine(lit.)
• InChIKey: UWCVGPLTGZWHGS-PLBOZXOQNA-N
• SMILES: C12=C3C=CC=C1[C@@]1([H])C[C@H](CN(CCC)[C@]1([H])CC2=CN3)CSC.S(=O)(=O)(O)C |&1:6,9,15,r|
• CAS DataBase Reference: 66104-23-2(CAS DataBase Reference)

Description and Uses

Pergolide mesylate is a potent, long-acting dopamine agonist useful in the treatment of Parkinson’s disease and hyperprolactinemia, Compared with lergotrile, pergolide mesylate has shown less toxicity and lower propensity for inducing psychosis.

dopamine receptor agonist, anti-Parkinson's agent

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H300
• Precautionary statements: P301+P330+P331+P310
• Hazard Codes: T+
• Risk Statements: 28
• Safety Statements: 28-36/37-45
• RIDADR: UN 1544
• WGK Germany: 3
• RTECS: KE6345000
• HS Code: 2939690000