M3451235
Lofexidinehydrochloride , 98% , 21498-08-8
Synonym(s):
2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride;Britlofex;Lofetensin;Loxacor
CAS NO.：21498-08-8
Empirical Formula: C11H13Cl3N2O
Molecular Weight: 295.59
MDL number: MFCD00917022
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB614.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 230-232°C |
| storage temp. | -20°C Freezer |
| solubility | H2O: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| InChI | InChI=1S/C11H12Cl2N2O.ClH/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13;/h2-4,7H,5-6H2,1H3,(H,14,15);1H |
| InChIKey | DWWHMKBNNNZGHF-UHFFFAOYSA-N |
| SMILES | C1(=C(Cl)C=CC=C1Cl)OC(C)C1=NCCN1.Cl |
| CAS DataBase Reference | 21498-08-8(CAS DataBase Reference) |
Description and Uses
a2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301+P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| Toxicity | LD50 in mice, rats, dogs (mg/kg): between 74-147 orally (all species); between 8-18 i.v. (all species) (Tsai) |
