M3269335
Indapamide , ≥98% , 26807-65-8
Synonym(s):
N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline;Indapamide
CAS NO.：26807-65-8
Empirical Formula: C16H16ClN3O3S
Molecular Weight: 365.83
MDL number: MFCD00079375
EINECS: 248-012-7
| Pack Size | Price | Stock | Quantity |
| 1g | RMB108.80 | In Stock |
|
| 5g | RMB294.40 | In Stock |
|
| 25g | RMB733.60 | In Stock |
|
| 100g | RMB2252.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 160-162°C |
| Boiling point: | 110.4°C (rough estimate) |
| alpha | -0.8～+0.8°(D/20℃) (c=5, C2H5OH) |
| Density | 1.2895 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Practically insoluble in water, soluble in ethanol (96 per cent). |
| pka | pKa (25°) 8.8 ± 0.2 |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in ethanol. Insoluble in water |
| Merck | 14,4935 |
| BCS Class | 1 |
| InChIKey | NDDAHWYSQHTHNT-UHFFFAOYSA-N |
| CAS DataBase Reference | 26807-65-8(CAS DataBase Reference) |
| EPA Substance Registry System | Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)- (26807-65-8) |
Description and Uses
Indapamide is a derivative of benzolsulfonamide and its mechanism of action is analogous to that of thiazides. It is intended for lowering arterial blood pressure and as an adjuvant drug for treating edema caused by cardiac insufficiency.
Used as an antihypertensive. Diuretic.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361d-H362 |
| Precautionary statements | P202-P260-P263-P264-P270-P308+P313 |
| WGK Germany | 2 |
| RTECS | CV2451200 |
| HS Code | 2935904000 |
| Toxicity | LD50 in rats, mice, guinea pigs (mg/kg): 393-421, 410-564, 347-416 i.p.; 394-440, 577-635, 272-358 i.v.; >3000 all species orally (Kyncl) |
