GS-5816 , 99% , 1377049-84-7
CAS NO.：1377049-84-7
Empirical Formula: C49H54N8O8
Molecular Weight: 883
MDL number: MFCD28411371
EINECS: 1592732-453-0
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB404.00 | In Stock |
|
| 100mg | RMB1824.00 | In Stock |
|
| 500mg | RMB4680.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >170oC (dec.) |
| Density | 1.314±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (>25 mg/ml) |
| form | solid |
| pka | 10.75±0.46(Predicted) |
| color | Pale yellow |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Description and Uses
Velpatasvir (1377049-84-7) is an extremely potent pan-genotypic hepatitis C virus (HCV) NS5A inhibitor.1 It is a component of Epclusa? and Vosevi?, two clinically useful medications with 98% and 97%, respectively, cure rates for HCV.? It displayed EC50’s for GTs 1-4, 6a ranging from 6-16 pM, GT5a at 75 pM, and GT6e at 130 pM. Velpatasvir also displayed an excellent barrier to viral resistance. It has been shown in silico, that velpatasvir binds to the SARS-CoV-2 spike protein and may be a potential therapeutic.2
Velpatasvir is a NS5A inhibitor in patients with hepatitis C (HCV) infection.
