FlavinAdenineDinucleotide , 97% , 146-14-5

CAS NO.：146-14-5

Empirical Formula: C27H33N9O15P2

Molecular Weight: 785.55

MDL number: MFCD00041835

EINECS: 205-663-1

PRODUCT Properties

• Density: 2.08±0.1 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: Methanol (Slightly, Heated), Water (Slightly)
• form: powder
• pka: 1.13±0.50(Predicted)
• color: orange
• Merck: 4091
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChIKey: VWWQXMAJTJZDQX-ZGGJIJKNNA-N

Description and Uses

Flavin adenine dinucleotide (FAD) is a cofactor for cytochrome-b5 reductase, the enzyme that maintains hemoglobin in its functional reduced state, and for glutathione reductase. This enzyme also protects erythrocytes from oxidative damage. FAD is a redox cofactor of several essential reactions in metabolism. This cofactor exists in two redox states, with FAD and FADH2 being the oxidized and reduced forms, respectively. FAD is formed of a riboflavin moiety (vitamin B2) coupled to a phosphate group of an ADP molecule. The reaction starts with the conversion of riboflavin into flavin mononucleotide catalyzed by riboflavin kinase. Flavin mononucleotide is subsequently transformed into FAD by adding an AMP moiety from ATP catalyzed by FAD-synthase. Therefore, FAD availability is tightly dependent on vitamin B2 and energy metabolism[1].

Labelled Flavine Adenine xidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P302+P352-P362+P364
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: AU7470000
• F: 8-10-21
• HS Code: 29349990