Potassiumorotate , 98% , 24598-73-0
Synonym(s):
6-Carboxy-2,4-dihydroxypyrimidine;Uracil-6-carboxylic acid
CAS NO.：24598-73-0
Empirical Formula: C5H3KN2O4
Molecular Weight: 194.19
MDL number: MFCD00039118
EINECS: 246-341-0
| Pack Size | Price | Stock | Quantity |
| 25g | RMB160.00 | In Stock |
|
| 100g | RMB494.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >300°C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Base (Slightly) |
| form | Solid |
| color | White to Light Yellow |
| Stability: | Hygroscopic |
| LogP | -0.928 (est) |
Description and Uses
Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Safety
| WGK Germany | 2 |
| RTECS | RM3201500 |
| HazardClass | IRRITANT |
