M0256435
BuparlisibHydrochloride , ≥98% , 1312445-63-8
CAS NO.：1312445-63-8
Empirical Formula: C18H22ClF3N6O2
Molecular Weight: 446.854
MDL number: MFCD22124511
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB829.60 | In Stock |
|
| 10mg | RMB1339.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | ≥44.7 mg/mL in DMSO; ≥52.8 mg/mL in H2O with gentle warming; ≥96 mg/mL in EtOH with gentle warming |
| form | solid |
| color | White to yellow |
| InChI | InChI=1S/C18H21F3N6O2.ClH/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27;/h9-11H,1-8H2,(H2,22,23);1H |
| InChIKey | DGPLYAXBXJXEID-UHFFFAOYSA-N |
| SMILES | C(C1=CC(N)=NC=C1C1=NC(N2CCOCC2)=NC(N2CCOCC2)=C1)(F)(F)F.Cl |
Description and Uses
NVP-BKM 120-d16 Hydrochloride is the salt, labeled analogue of NVP-BKM 120 (N925760), a novel anti-tumor active compound that is selective in that it inhibits specifically PI3 kinase activating cell death in glioma cells. Glioma cells being those that proliferate from tumors in the brain or the spine.
Safety
| Symbol(GHS) |    GHS08,GHS09,GHS06 |
| Signal word | Danger |
| Hazard statements | H372-H400-H341-H300-H411 |
| Precautionary statements | P260-P264-P270-P314-P501-P264-P270-P301+P310-P321-P330-P405-P501-P273-P391-P501-P201-P202-P281-P308+P313-P405-P501 |
