M0212735
BIBF1202? , ≥99% , 894783-71-2
Pack Size | Price | Stock | Quantity |
1mg | RMB1732.80 | In Stock |
|
5mg | RMB6840.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | >216°C (dec.) |
Boiling point: | 759.5±60.0 °C(Predicted) |
Density | 1.331±0.06 g/cm3(Predicted) |
storage temp. | Refrigerator |
solubility | Aqueous Base (Slightly, Heated) |
pka | 3.94±0.20(Predicted) |
form | Solid |
color | Light Yellow to Yellow |
Description and Uses
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.