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M0212735

BIBF1202? , ≥99% , 894783-71-2

CAS NO.:894783-71-2

Empirical Formula: C30H31N5O4

Molecular Weight: 525.6

MDL number:

Pack Size Price Stock Quantity
1mg RMB1732.80 In Stock
5mg RMB6840.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >216°C (dec.)
Boiling point: 759.5±60.0 °C(Predicted)
Density  1.331±0.06 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  Aqueous Base (Slightly, Heated)
pka 3.94±0.20(Predicted)
form  Solid
color  Light Yellow to Yellow

Description and Uses

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.

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