PRODUCT Properties
Melting point: | 201-203℃ |
alpha | D20 -135.4° |
Boiling point: | 535.8±50.0 °C(Predicted) |
Density | 1.29 |
solubility | DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 5 mg/ml; Ethanol: slightly soluble |
form | A solid |
pka | 14.20±0.60(Predicted) |
color | White to off-white |
Description and Uses
Songorine is an extract from the Aconitum flavum root and may act as an inhibitor of JNK and p53 enhancing stimulation of fibroblast colony/cluster formation and proliferative activity of mesosomal precursors.
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H310-H300-H330 |
Precautionary statements | P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
Toxicity | LD50 in mice (mg/kg): 1575 orally, 630 s.c., 485 i.p., 142.5 i.v.; in rats (mg/kg): 407.5 i.p. (Bisset) |