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LN9445658

Spiroxamine , 118134-30-8

Synonym(s):
N-Ethyl-N-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine

CAS NO.:118134-30-8

Empirical Formula: C18H35NO2

Molecular Weight: 297.48

MDL number: MFCD03095708

Pack Size Price Stock Quantity
500mg RMB1820.00 In Stock
1g RMB2794.40 In Stock
2g RMB5588.80 In Stock
5g RMB8377.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: <25 °C
Boiling point: bp 120° at 0.067 hPa
Density  0.96±0.1 g/cm3(Predicted)
refractive index  nD20 1.4662
Flash point: 147 °C
storage temp.  0-6°C
solubility  Chloroform: Slightly Soluble
pka 6.9(at 25℃)
form  Liquid
color  Colorless to light yellow
Stability: Hygroscopic
LogP 4.880 (est)

Description and Uses

Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ14 reductase/Δ8→Δ7 isomerase. It inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines (EC50s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC20 = 9.29 μM).

Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H317-H361d-H373-H410
Precautionary statements  P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
Hazard Codes  Xn,N
Risk Statements  20/21/22-38-43-50/53
Safety Statements  36/37/39-46-60-61
RIDADR  UN3082 9/PG 3
WGK Germany  3
Toxicity LD50 in rats (mg/kg): ~595 orally; >1600 dermally; LC50 in rats (mg/m3): ~2772 by inhalation; LC50 (96 hr) in rainbow trout: 18.5 mg/l (Dutzmann)

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