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LN8845946

1-O-hexadecyl-sn-glycerol(HG) , 99% , 506-03-6

Synonym(s):
1-O-hexadecyl-sn-glycerol (HG)

CAS NO.:506-03-6

Empirical Formula: C19H40O3

Molecular Weight: 316.52

MDL number: MFCD00151171

EINECS: 208-026-6

Pack Size Price Stock Quantity
50mg RMB948.80 In Stock
100mg RMB1660.80 In Stock
500mg RMB6205.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 64°
alpha  D20 +3.0° (c = 1.16 in chloroform)
Boiling point: bp0.005 120°
Density  1.0054 (rough estimate)
refractive index  1.4410 (estimate)
storage temp.  -15°C
solubility  DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml
form  A crystalline solid
pka 13.68±0.20(Predicted)
LogP 6.702 (est)

Description and Uses

1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.

1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.

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