PRODUCT Properties
| Boiling point: | 134-135 °C(Press: 11 Torr) |
| Density | 0.9631 g/cm3 |
| solubility | Dichloromethane; Methanol |
| form | Oil |
| color | Yellow |
Description and Uses
1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H335-H302-H315-H319-H312-H332 |
| Precautionary statements | P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
