Methylprednisoloneaceponate , 95+% , 86401-95-8
CAS NO.：86401-95-8
Empirical Formula: C27H36O7
Molecular Weight: 472.57
MDL number: MFCD00866150
EINECS: 608-705-0
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB484.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 105 - 108°C |
| Boiling point: | 595.8±50.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly) |
| form | Solid |
| pka | 14.05±0.70(Predicted) |
| color | White to Off-White |
| InChIKey | DALKLAYLIPSCQL-TXWHWSFMNA-N |
| SMILES | O(C(CC)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)=O |&1:5,15,16,18,25,27,28,30,r| |
Description and Uses
Methylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.
Methylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
