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LN6870838

Captopril-Disuphide , 64806-05-9

Synonym(s):
(2S)-1-[(2S)-3-(Acetylsulfanyl)-2-methylpropanoyl]pyrrolidine-2-carboxylic acid;N-[3-(Acetylthio)-(2S)-methylpropionyl]-L-proline;1,1′-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline;Acetylcaptopril

CAS NO.:64806-05-9

Empirical Formula: C18H28N2O6S2

Molecular Weight: 432.55

MDL number: MFCD08063643

Pack Size Price Stock Quantity
50mg RMB200.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 224-226°C
Boiling point: 714.8±60.0 °C(Predicted)
Density  1.383±0.06 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form  Solid
pka 3.29±0.20(Predicted)
color  White to Off-White

Description and Uses

Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril . Captopril disulfide is the main degradation product of captopril and is formed by oxidation. It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.).

Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.

Safety

WGK Germany  3
HS Code  2933999552

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