Home Categories Analytical Chemistry (±)-Lisofylline
LN6629158

(±)-Lisofylline , ≥98% , 6493-06-7

CAS NO.:6493-06-7

Empirical Formula: C13H20N4O3

Molecular Weight: 280.32

MDL number: MFCD00867573

Pack Size Price Stock Quantity
10mg RMB972.00 In Stock
25mg RMB1564.00 In Stock
50mg RMB2988.00 In Stock
100mg RMB5304.00 In Stock
250mg RMB8223.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 123-125°C
Boiling point: 511.2±56.0 °C(Predicted)
Density  1.32±0.1 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  DMSO: soluble
form  solid
pka 15.22±0.20(Predicted)
color  white
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Description and Uses

Lisofylline (6493-06-7, racemic) displays anti-inflammatory activity. Regulates immune cell function and autoimmune response by inhibition of IL-12 signalling and cytokine production.1 Protects pancreatic beta cells and prevents type I diabetes in non-obese diabetic mice.2 Lisofylline reduces LPS-induced TNF alpha levels in CD-1 mice.3?Cell permeable.

A major oxidative metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.

Safety

WGK Germany  3

RELATED PRODUCTS