chloramphenicolpalmitate , Analysis standard reagent , 530-43-8

Synonym(s):
Chloramphenicol palmitate

CAS NO.：530-43-8

Empirical Formula: C27H42Cl2N2O6

Molecular Weight: 561.54

MDL number: MFCD00083597

EINECS: 208-477-9

PRODUCT Properties

• Melting point: 90 C
• alpha: D26 +24.6° (c = 5 in ethanol)
• Boiling point: 691.6±55.0 °C(Predicted)
• Density: 1.2354 (rough estimate)
• refractive index: 1.7350 (estimate)
• storage temp.: Store at RT.
• solubility: DMSO (Slightly), Ethanol (Sparingly), Ethyl Acetate (Slightly)
• form: Solid
• pka: 10.69±0.46(Predicted)
• color: White to Off-White
• Water Solubility: 8.423ug/L(25 ºC)
• λmax: 271nm(EtOH)(lit.)
• Merck: 14,2077
• BRN: 2826438
• Stability: Hygroscopic

Description and Uses

Chloramphenicol palmitate is an orally bioavailable ester prodrug form of the antibiotic chloramphenicol. It is hydrolyzed in the small intestine to release chloramphenicol. Formulations containing chloramphenicol palmitate were previously used in the treatment of severe bacterial infections.

antibacterial, antirickettsial

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H351
• Precautionary statements: P280
• Hazard Codes: Xn
• Risk Statements: 40-36/37/38-20/21/22
• Safety Statements: 36/37-36-26
• WGK Germany: 3
• RTECS: RT4735000
• HS Code: 29414000