AG-183 , ≥98% , 122520-90-5
Synonym(s):
2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB812.00 | In Stock |
|
| 25mg | RMB1693.60 | In Stock |
|
| 50mg | RMB3004.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 275 °C |
| Boiling point: | 788.2±60.0 °C(Predicted) |
| Density | 1.591±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ≤20mg/ml in DMSO;20mg/ml in dimethyl formamide |
| form | Orange solid. |
| pka | 8.46±0.15(Predicted) |
Description and Uses
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-
Tyrphostin 51 is a potent inhibitor of EGFRK activity showing mixed competitive inhibition with ATP and substrate1-3..
Safety
| Symbol(GHS) |  GHS07 |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a |
| WGK Germany | 3 |
| HazardClass | 6.1 |
