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LN436285

Ibandronate , 99% , 114084-78-5

CAS NO.:114084-78-5

Empirical Formula: C9H23NO7P2

Molecular Weight: 319.23

MDL number: MFCD00868772

Pack Size Price Stock Quantity
1g RMB114.40 In Stock
5g RMB321.60 In Stock
10g RMB630.40 In Stock
15g RMB916.80 In Stock
25g RMB1091.20 In Stock
50g RMB2073.60 In Stock
100g RMB3152.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 113-115°C
Boiling point: 587.8±60.0 °C(Predicted)
Density  1.449±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
pka 1.60±0.10(Predicted)
color  White to Off-White
Stability: Hygroscopic

Description and Uses

This third generation biphosphonate was launched in Austria and Germany for the treatment of bone disorders such as hypercalcemia in malignancy and ostedysis, Paget's disease and osteoporosis. It does not effect bone mineralization, therefore, the potential risk of osteomalacia is prevented. This was a problem with first generation derivatives. While the exact mode of action is not understood, they are inhibitors of osteroclast mediated bone resorption. These compounds strongly interact with hydroxyapatite crystals and have a half-life in the skeleton of several years. Despite this observation ibandronate was well tolerated and safe.

A labeled biphosphonate bone resorption inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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