Home Categories Analytical Chemistry cis-Entacapone
LN4321049

cis-Entacapone , ≥98% , 145195-63-7

Synonym(s):
(Z)-Entacapone;(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide

CAS NO.:145195-63-7

Empirical Formula: C14H15N3O5

Molecular Weight: 305.29

MDL number: MFCD00869878

Pack Size Price Stock Quantity
1mg RMB1296.00 In Stock
5mg RMB4364.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 142-144°C
Boiling point: 526.6±50.0 °C(Predicted)
Density  1.392±0.06 g/cm3(Predicted)
storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility  Dichloromethane (Slightly), Methanol (Slightly)
pka 5.15±0.50(Predicted)
color  Yellow to Orange

Description and Uses

cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone . It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.

cis-Entacapone (Entacapone EP Impurity A) is the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian.

Safety

HS Code  2926900005

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