Unoprostoneisopropylester , ≥98% , 120373-24-2
CAS NO.：120373-24-2
Empirical Formula: C25H44O5
Molecular Weight: 424.61
MDL number: MFCD00886951
EINECS: 1312995-182-4
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB628.00 | In Stock |
|
| 5mg | RMB2544.00 | In Stock |
|
| 10mg | RMB4516.00 | In Stock |
|
| 50mg | RMB18064.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 546.3±45.0 °C(Predicted) |
| Density | 1.019±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| pka | 14.79±0.70(Predicted) |
| color | Clear Colourless |
Description and Uses
Unoprostone isopropyl ester, a novel prostaglandin derivative, was launched in Japan as eye drops for the treatment of glaucoma and ocular hypertension. In animal and human studies, a single drop of unoprostone isopropyl ester induced significant decrease in intraocular pressure without systemic effects, myosis or mydriasis. Unlike prostaglandin analogs such as PGF2α, unoprostone isopropyl ester does not cause irritation in outer segment of the eye or significant changes in aqueous protein concentration and corneal endothelial permeability. Unoprostone isopropyl ester is suggested to act by increasing uveoscleral outflow or by decreasing episcleral venous pressure, resulting in ocular hypotension.
Isopropyl unoprostone is an antiglaucoma,it is used in treatment of ocular hypertension.
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225-H302-H319-H336 |
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P330-P303+P361+P353-P304+P340-P305+P351+P338-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 |
