Home Categories Biochemical Engineering MuristeroneA
LN3142549

MuristeroneA , ≥98% , 38778-30-2

CAS NO.:38778-30-2

Empirical Formula: C27H44O8

Molecular Weight: 496.63

MDL number: MFCD00056450

Pack Size Price Stock Quantity
1mg RMB3928.00 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 707.2±60.0 °C(Predicted)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  Soluble in DMSO
form  solid
pka 11.78±0.70(Predicted)
color  white

Description and Uses

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Safety

WGK Germany  3

RELATED PRODUCTS