MuristeroneA , ≥98% , 38778-30-2
Pack Size | Price | Stock | Quantity |
1mg | RMB3928.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 707.2±60.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | Soluble in DMSO |
form | solid |
pka | 11.78±0.70(Predicted) |
color | white |
Description and Uses
Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.
Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.
Safety
WGK Germany | 3 |