LN2217730
97% , 674-82-8
CAS NO.：674-82-8
Empirical Formula: C4H4O2
Molecular Weight: 84.07
MDL number: MFCD00005173
EINECS: 211-617-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -7.5°C |
| Boiling point: | 69-70 °C100 mm Hg(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| vapor density | 2.9 (vs air) |
| vapor pressure | 7.9 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 95 °F |
| storage temp. | 2-8°C |
| CAS DataBase Reference | 674-82-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Oxetanone, 4-methylene-(674-82-8) |
| EPA Substance Registry System | Diketene (674-82-8) |
Description and Uses
Diketene is used as a reactant in the manufacture of paper and control of its sizing. In addition its used in the preparation of potent and selective inhibitor of histone methyltransferase EZH2 in the treatment of B-Cell lymphomas.
Safety
| Symbol(GHS) |   GHS02,GHS06 |
| Signal word | Danger |
| Hazard statements | H226-H302-H331 |
| Precautionary statements | P261-P301+P312+P330-P304+P340+P312-P403+P233-P403+P235 |
| Hazard Codes | Xn |
| Risk Statements | 10-20-40-36/37/38 |
| Safety Statements | 3-36/37-33-24/25-23-16-26 |
| RIDADR | UN 2929 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | RQ8225000 |
| F | 19-21-27 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| Hazardous Substances Data | 674-82-8(Hazardous Substances Data) |
| IDLA | 7.6 ppm |
