![1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone](https://img.chemicalbook.com/CAS/20200401/GIF/1839150-56-9.gif)
LN-985032
1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone , 98% HPLC , 1839150-56-9
CAS NO.：1839150-56-9
Empirical Formula: C26H29N7O2
Molecular Weight: 471.55
MDL number: MFCD30182360
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 703.2±60.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 8.24±0.28(Predicted) |
Description and Uses
CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. In vivo CHMFL-FLT3-122 significantly suppressed the tumor growth in MV4-11 cell inoculated xenograft model (50 mg/kg) without exhibiting obvious toxicity.
