LN-965215
L-744,832 , >98% HPLC , 1177806-11-9
Synonym(s):
(2S)-2-[[(2S)-2-[(2S,3S)-2-[(2R)-2-Amino-3-mercaptopropyl]amino]-3-methylpentyl]oxy]-1-oxo-3-phenylpropyl]amino]-4-(methylsulfonyl)-butanoic Acid 1-Methylethyl Ester, L-744,382;L-744,832 - CAS 1177806-11-9 - Calbiochem
CAS NO.:1177806-11-9
Empirical Formula: C26H47Cl2N3O6S2
Molecular Weight: 632.7
MDL number: MFCD07357323
Update time: 2023-04-23
PRODUCT Properties
Melting point: | 165-168°C |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | White solid |
color | White |
Description and Uses
L-744,832 is ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expressoin and arrests cells at G1. Causes enhanced mitotic