Home Categories L-744,832
LN-965215

L-744,832 , >98% HPLC , 1177806-11-9

Synonym(s):
(2S)-2-[[(2S)-2-[(2S,3S)-2-[(2R)-2-Amino-3-mercaptopropyl]amino]-3-methylpentyl]oxy]-1-oxo-3-phenylpropyl]amino]-4-(methylsulfonyl)-butanoic Acid 1-Methylethyl Ester, L-744,382;L-744,832 - CAS 1177806-11-9 - Calbiochem

CAS NO.:1177806-11-9

Empirical Formula: C26H47Cl2N3O6S2

Molecular Weight: 632.7

MDL number: MFCD07357323

Update time: 2023-04-23

PRODUCT Properties

Melting point: 165-168°C
storage temp.  -20°C Freezer
solubility  DMSO (Slightly), Methanol (Slightly)
form  White solid
color  White

Description and Uses

L-744,832 is ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expressoin and arrests cells at G1. Causes enhanced mitotic

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