Home Categories 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
LN-943231

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin , 76877-33-3

Synonym(s):
1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-;Anti-Carboxypeptidase M precursor antibody produced in rabbit;Carboxypeptidase M;CPM

CAS NO.:76877-33-3

Empirical Formula: C24H22N2O4

Molecular Weight: 402.44

MDL number: MFCD00077334

Update time: 2023-04-23

PRODUCT Properties

Melting point: 220-223°C
Boiling point: 618.7±55.0 °C(Predicted)
Density  1.302±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO: soluble
pka 3.28±0.20(Predicted)
form  solid
color  yellow

Description and Uses

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.

(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
WGK Germany  3
10

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