![2-Pyridinecarboxamide, 6-fluoro-5-[4-[(5-fluoro-3,4-dihydro-2-methyl-3-oxo-6-quinoxalinyl)methyl]-1-piperazinyl]-N-methyl-](https://img.chemicalbook.com/CAS/20210305/GIF/2756333-39-6.gif)
LN-890332
2-Pyridinecarboxamide, 6-fluoro-5-[4-[(5-fluoro-3,4-dihydro-2-methyl-3-oxo-6-quinoxalinyl)methyl]-1-piperazinyl]-N-methyl- , 98% HPLC , 2756333-39-6
Update time: 2023-04-23
PRODUCT Properties
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| pka | 8.17±0.20(Predicted) |
| form | Solid |
| color | White to yellow |
Description and Uses
AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD+?breast cancer and advanced solid malignancies research[1].