LN-880314
Acebutolol , 99.9% , 37517-30-9
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 119-123°C |
| Boiling point: | 472.9°C (rough estimate) |
| Density | 1.1748 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | DMF: 10 mg/mL,DMSO: 5 mg/mL,Ethanol: 5 mg/mL,PBS (pH 7.2): 0.3 mg/mL |
| form | A solid |
| pka | pKa 9.40 (Uncertain) |
| color | Crystals |
| Water Solubility | 259 mg/L |
| CAS DataBase Reference | 37517-30-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Acebutolol(37517-30-9) |
| EPA Substance Registry System | Butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- (37517-30-9) |
Description and Uses
Acebutol is 3′-acetyl-4′-[2-hydroxy-3-(iso-propylamino)propoxy] butyranilide (12.1.6) [9,10].Acebutol is a selective β1-adrenoblocker. It possesses antianginal, antihypotensive, and antiarrhythmic action. It is used for arterial hypertension, preventing attacks of angina, and cardiac rhythm disturbances.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H362 |
| Precautionary statements | P201-P260-P263-P264-P270-P308+P313 |
| Toxicity | TDLo orl-wmn: 152 mg/kg:CVS,BPR JTCTDW 20,69,83 |
