LN-834914
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid , 0.97 , 402849-27-8
Update time: 2023-04-23
PRODUCT Properties
Melting point: | 159-163°C |
Density | 1.370±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Soncited) |
pka | 9.41±0.46(Predicted) |
form | Solid |
color | White to Pale Beige |
Description and Uses
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.