LN-821514
Bopindolol , 99.9% , 62658-63-3
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 117-120°C |
| Boiling point: | 557.0±50.0 °C(Predicted) |
| Density | 1.143±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 17.59±0.30(Predicted) |
| form | Solid |
| color | White to Pale Beige |
Description and Uses
Bopindolol is a potent, long-acting, non-selective β-adrenergic blocker related to pindolol and useful in the treatment of hypertension. Unlike many other agents of this type, it appears to have negligible effects on serum lipoproteins.
Bopindolol is an ester prodrug of Pindolol (P468000). Bopindolol is a long acting β-adrenoceptor blocking agent. Bopindolol displays antispasmogenic activity mediated by α1-adrenoceptors and 5-HT2 receptors.
Safety
| Toxicity | LD50 i.v. in mice: 17 mg/kg (Troxler, Seemann, 1977) |
