Home Categories (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
LN-687982

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide , 98% , 135729-78-1

CAS NO.:135729-78-1

Empirical Formula: C18H24N2O

Molecular Weight: 284.4

MDL number: MFCD27923863

Update time: 2023-04-23

PRODUCT Properties

Melting point: 157-159oC
Boiling point: 439.2±45.0 °C(Predicted)
Density  1.17
storage temp.  Refrigerator
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 14.75±0.20(Predicted)
color  White

Description and Uses

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

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