Home Categories Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)-
LN-626334

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)- , 0.95 , 681282-72-4

CAS NO.:681282-72-4

Empirical Formula: C17H27NO6

Molecular Weight: 341.4

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Boiling point: 534.7±35.0 °C(Predicted)
Density  1.406±0.06 g/cm3(Predicted)
pka 3.93±0.10(Predicted)

Description and Uses

Boc-3,5-dihydroxy-1-adamantyl-L-glycine is a reactant in the synthesis of Saxagliptin (S143500), a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

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