UNCARINE C , 98% , 5629-60-7
PRODUCT Properties
| Melting point: | 217-219℃ |
| Density | 1.33±0.1 g/cm3 (20 ºC 760 Torr) |
Description and Uses
Isolated from Uncaria pteropoda, this alkaloid is probably stereoisomeric withMitraphylline (q.v.). It forms colourless plates when crystallized from MeOH and has [α]29DJ 9 - 102.5° (c 1.0, CHC13). The ultraviolet spectrum in MeOH has an absorption maximum at 246 mp. with a shoulder at 280 mp.. A crystalline picrate, m.p. 143-6°C; [α]D - 9.6° (c 0.5, EtOH) and a methiodide, m.p. 209-211°C after softening at 204°C; [α]D - 149° (c 0.53, EtOH) have been prepared. A solution of the alkaloid in pyridine forms an equilibrium mixture with 70 per cent isopteropodine when heated.
Uncarine C is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
