LN-585027
Rugulosin, 8,8'-dihydroxy-, (1S,1'S,2R,2'R,3S,3'S,9aR,9'aR)- , 21884-44-6
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 278°C (rough estimate) |
| Boiling point: | 555.89°C (rough estimate) |
| Density | 1.3474 (rough estimate) |
| refractive index | 1.6480 (estimate) |
| pka | 4.20±1.00(Predicted) |
| IARC | 3 (Vol. 10, Sup 7) 1987 |
Description and Uses
(-)-Luteoskyrin has a wide range of antibacterial activity, such as against malaria (with an IC50 of 0.51 μg/mL), tuberculosis (MIC of 6.25 μg/mL), and it also shows antibacterial effects (with MIC for Gram-positive bacteria ranging from 0.39 to 1.56 μg/mL, and for Gram-negative bacteria from 3.13 to 12.50 μg/mL), as well as antifungal activity (with MIC against plant pathogens ranging from 3.13 to 50μg/mL). (-)-Luteoskyrin exhibits cytotoxicity against NCI-H187 cells, with an IC50 range of 0.16–17.99 μg/mL[1].
Safety
| Hazardous Substances Data | 21884-44-6(Hazardous Substances Data) |