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LN-539514

Isoniazid-D4 , 99.9% , 774596-24-6

CAS NO.:774596-24-6

Empirical Formula: C6H7N3O

Molecular Weight: 137.14

MDL number: MFCD09840815

Update time: 2023-04-23

PRODUCT Properties

Melting point: 171.40C
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Pale Beige

Description and Uses

Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).

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