LN-527333
Loperamide , 99 , 53179-11-6
CAS NO.：53179-11-6
Empirical Formula: C29H33ClN2O2
Molecular Weight: 477.04
MDL number: MFCD00600388
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 647.2±55.0 °C(Predicted) |
| Density | 1.187±0.06 g/cm3(Predicted) |
| pka | pKa 8.66(H2O) (Uncertain) |
| BCS Class | 4 |
| LogP | 2.641 at 25℃ and pH6.95 |
| CAS DataBase Reference | 53179-11-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Loperamide(53179-11-6) |
Description and Uses
Loperamide is presently used more often as an antidiarrheal drug than as an analgesic, and it is also included in the list of over-the-counter drugs because of its insignificant action on the CNS. It reduces intestinal smooth muscle tone and motility as a result of binding to intestinal opiate receptors. It is used for symptomatic treatment of severe and chronic diarrhea of various origins. The most popular synonym for loperamide is imodium.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| Hazardous Substances Data | 53179-11-6(Hazardous Substances Data) |
