(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione , 1486466-31-2

Synonym(s):
Clobetasol impurity J (PhEur);Clobetasol Related Compound A (USP)

CAS NO.：1486466-31-2

Empirical Formula: C25H30ClFO4

Molecular Weight: 448.95

MDL number: MFCD11558988

Update time: 2023-04-23

PRODUCT Properties

Melting point:	>276°C (dec.)
Boiling point:	563.7±50.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
pka	12.96±0.70(Predicted)
color	White to off-White

Description and Uses

(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.

Safety

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H360Df-H373-H413
Precautionary statements	P201-P308+P313
Hazard Codes	T
Risk Statements	61-48/20/21-53-62
Safety Statements	53-36/37-45
WGK Germany	3