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LN-402733

Flumethasone 21-pivalate , 2002-29-1

Synonym(s):
6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate);Flumetasone 21-pivalate;NSC 107680

CAS NO.:2002-29-1

Empirical Formula: C27H36F2O6

Molecular Weight: 494.57

MDL number: MFCD00079287

Update time: 2023-04-23

PRODUCT Properties

Melting point: >263°C (dec.)
Boiling point: 600.3±55.0 °C(Predicted)
Density  1.27±0.1 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  dioxane: soluble4.0ML, clear, colorless to very faintly yellow (50 mg + 4.0 mL dioxane)
form  solid
pka 11.86±0.70(Predicted)
color  White to Off-White
optical activity [α]25/D 71.0 to 82.0°, c = 1 in dioxane
CAS DataBase Reference 2002-29-1(CAS DataBase Reference)
EPA Substance Registry System Flumethasone-21-pivalate (2002-29-1)

Description and Uses

An anti-inflammatory anti-itching corticosteroid found in topical creams.

Safety

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  Xn
Risk Statements  40
Safety Statements  22-36
WGK Germany  3
RTECS  TU3832010
HS Code  2937220000
Toxicity mouse,LD50,oral,> 5gm/kg (5000mg/kg),Drugs in Japan Vol. 6, Pg. 705, 1982.

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