LN-381377
4-Nitro-2-phenoxyphenol , 99% , 70995-08-3
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 63℃ (ligroine ) |
| Boiling point: | 358.2±37.0 °C(Predicted) |
| Density | 1.357±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, Inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 5.76±0.16(Predicted) |
| color | Pale Yellow to Light Yellow |
Description and Uses
4-?Nitro-?2-?phenoxyphenol is a impurity of Nimesulide (N477500), antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production. Also used in the preparation of benzoxirenes and the synthesis of trioxonins.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
