LN-252734
6,8-DIFLUORO-7-HYDROXY-4-METHYLCOUMARIN , 0.95 , 215868-23-8
Update time: 2023-04-23
PRODUCT Properties
Melting point: | 213-215°C |
Boiling point: | 332.3±42.0 °C(Predicted) |
Density | 1.494±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Insoluble in water; soluble in chloroform,
N,N-dimethylformamide, dimethyl sulfoxide |
pka | 4.7, (at 22℃)
(calcd.) 5.50 ± 0.20, most acidic, temperature:
25 °C |
form | Off-White to Pale Yellow Soild |
color | Colorless needles; white solid |
λmax | 358 nm (Buffers pH 10.0, pH 9.0) |
Stability: | Hygroscopic |
Major Application | Detecting/quantifying/measuring metals (beryllium, chromium, lead) |
Biological Applications | Amplifying/detectingnucleic acid sequences; analyzing peptides, sugarchains; detecting bacteria; detecting/quantifyingnucleic acids; a substrate for measuring acylprotein thioesterase (APT) activity,, α-amylaseactivity, aryl sulfatases activity, β-galactosidasesactivity,,, guanidinobenzoatase activity, β-lactamaseactivity, lipase activity, phosphatases activity,,phospholipase LYPLAL activity, protein kinasesactivity, xylanase activity; diagnosing/treatingtraumatic brain injury; treating amyloidogenic disease;as temperature sensor, |
Description and Uses
6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU) was used for the diagnostic detection of natural killer cell-activity.