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LN-244421

Isoproterenol , 0.99 , 7683-59-2

CAS NO.:7683-59-2

Empirical Formula: C11H17NO3

Molecular Weight: 211.26

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Melting point: 170.5°C
Boiling point: 350.94°C (rough estimate)
Density  1.1240 (rough estimate)
refractive index  1.5718 (estimate)
pka 8.64(at 25℃)
NIST Chemistry Reference 3,4-Dihydroxy-«alpha»-(isopropylaminomethyl)-benzyl alcohol(7683-59-2)

Description and Uses

Isoproterenol is a representative of the sympathomimetic drugs with high selectivity to β- adrenoreceptors. As was already noted, the addition to compounds of a bulky iso-propyl or tert-butyl group at the nitrogen atom of the β-phenylethylamino skeleton is associated with higher affinity to β-adrenergic receptive regions than to α-adrenergic. Isoproterenol is devoid of significant α-adrenergic agonistic action. Activation of β1-adrenergic receptors in the heart increases positive chronotropic and ionotropic action. Peripheral vascular resistance is increased by the widening of blood vessels, primarily in skeletal muscle, but also in renal and mesenteric blood circulation, which is caused by the β2-adrenergic system.

Isoproterenol is used in bronchospasms, asthma, cardiac block, and shock.

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