LN-244331
1,3,2-Dioxaborolane-2-methanamine, α-butyl-4,4,5,5-tetramethyl-, (αR)- , NLT 98% , 1259365-04-2
Update time: 2023-04-23
PRODUCT Properties
Boiling point: | 246.8±23.0 °C(Predicted) |
Density | 0.92±0.1 g/cm3(Predicted) |
pka | 10.91±0.35(Predicted) |
Description and Uses
(R)-1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pentan-1-amine is an impurity in the synthesis of Bortezomib(B675700) which is a reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.