LN-209714
mexazolam , 99.9% , 31868-18-5
CAS NO.：31868-18-5
Empirical Formula: C18H16Cl2N2O2
Molecular Weight: 363.24
MDL number: MFCD00866982
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 172-175° |
| Boiling point: | 522.2±50.0 °C(Predicted) |
| Density | 1.3817 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.69(at 25℃) |
| color | White to Off-White |
Description and Uses
Mexazolam is a benzodiazepine anxiolytic closely related to flutazolam. It is reported to be particularly effective against psychosomatic essential hypertension, peptic ulcer, irritable colon and autonomic dystonia.
Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway.
Safety
| Toxicity | LD50 in male, female mice; male, female rats (mg/kg): 4687, 4571, 810, 4500 orally; >6000, >6000, >4000, >4000 i.p. or s.c. (Masuda) |
