F418021
4-(Dimethylamino)antipyrine , 98+ , 58-15-1
Synonym(s):
4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one;Aminopyrine
CAS NO.:58-15-1
Empirical Formula: C13H17N3O
Molecular Weight: 231.29
MDL number: MFCD00003142
EINECS: 200-365-8
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 107-109 °C(lit.) |
Boiling point: | 373.38°C (rough estimate) |
Density | 1.0744 (rough estimate) |
refractive index | 1.6140 (estimate) |
storage temp. | Refrigerator |
solubility | DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
pka | pKa 5.0 (Uncertain) |
form | Crystalline Powder, Crystals and/or Chunks |
color | Off-white to brownish |
Water Solubility | 5.55 g/100 mL |
Sensitive | Air & Light Sensitive |
Merck | 14,474 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive. Degrades under the action of mild oxidizing agents in the presence of moisture or water. |
InChIKey | RMMXTBMQSGEXHJ-UHFFFAOYSA-N |
CAS DataBase Reference | 58-15-1(CAS DataBase Reference) |
NIST Chemistry Reference | Aminopyrine(58-15-1) |
EPA Substance Registry System | Aminopyrine (58-15-1) |
Description and Uses
Aminopyrine is used as an antipyretic and analgesic drug. It belongs to the pyrazolone derivatives having a most toxic and most dangerous analgesic effect and it is a non-narcotic drug. Due to strong adverse effects, its single medicine preparation is gradually replaced by compound preparation.
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301-H315-H319-H335 |
Precautionary statements | P261-P264-P270-P301+P310-P302+P352-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38-21/22 |
Safety Statements | 26-36-36/37/39 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | CD2625000 |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29331190 |
Hazardous Substances Data | 58-15-1(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 1.7 g/kg (Hart) |