Home Categories API 4-(Dimethylamino)antipyrine
F418021

4-(Dimethylamino)antipyrine , 98+ , 58-15-1

Synonym(s):
4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one;Aminopyrine

CAS NO.:58-15-1

Empirical Formula: C13H17N3O

Molecular Weight: 231.29

MDL number: MFCD00003142

EINECS: 200-365-8

Update time: 2022-07-08

PRODUCT Properties

Melting point: 107-109 °C(lit.)
Boiling point: 373.38°C (rough estimate)
Density  1.0744 (rough estimate)
refractive index  1.6140 (estimate)
storage temp.  Refrigerator
solubility  DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka pKa 5.0 (Uncertain)
form  Crystalline Powder, Crystals and/or Chunks
color  Off-white to brownish
Water Solubility  5.55 g/100 mL
Sensitive  Air & Light Sensitive
Merck  14,474
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive. Degrades under the action of mild oxidizing agents in the presence of moisture or water.
InChIKey RMMXTBMQSGEXHJ-UHFFFAOYSA-N
CAS DataBase Reference 58-15-1(CAS DataBase Reference)
NIST Chemistry Reference Aminopyrine(58-15-1)
EPA Substance Registry System Aminopyrine (58-15-1)

Description and Uses

Aminopyrine is used as an antipyretic and analgesic drug. It belongs to the pyrazolone derivatives having a most toxic and most dangerous analgesic effect and it is a non-narcotic drug. Due to strong adverse effects, its single medicine preparation is gradually replaced by compound preparation.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38-21/22
Safety Statements  26-36-36/37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  CD2625000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29331190
Hazardous Substances Data 58-15-1(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.7 g/kg (Hart)

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