Home Categories (S)-3-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoyl)-2,2-dimethyloxazolidine-4-carboxylicacid
BD9888355

(S)-3-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoyl)-2,2-dimethyloxazolidine-4-carboxylicacid , 98% , 878797-09-2

Synonym(s):
Fmoc-Tyr(tBu)-Ser(psiMe,Mepro)-OH

CAS NO.:878797-09-2

Empirical Formula: C34H38N2O7

Molecular Weight: 586.67

MDL number: MFCD11974986

Pack Size Price Stock Quantity
250mg RMB317.60 In Stock
1g RMB816.80 In Stock
5g RMB2844.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 795.6±60.0 °C(Predicted)
Density  1.238±0.06 g/cm3(Predicted)
storage temp.  Store at +2°C to +8°C.
pka 3.09±0.40(Predicted)
InChIKey DNJYPUYQFPFOKS-VMPREFPWSA-N
SMILES O1C[C@@H](C(O)=O)N(C(=O)[C@@H](NC(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CC2=CC=C(OC(C)(C)C)C=C2)C1(C)C

Description and Uses

Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH is mainly used in peptide synthesis. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-damaging proline-like TFA-labile oxazolidine. The reason for introducing the pseudoproline residue as a dipeptide is that it avoids the acylation of the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in a single step. The serine residue is regenerated in the normal trans fatty acid mediated cleavage reaction.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2934999090

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