(E)-1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)but-2-en-1-one , 97% , 94668-55-0

Synonym(s):
(N-Crotonyl)-(2R)-bornane-10,2-sultam;(2E)-1-[(3aS,6R,7aR)-Tetrahydro-8,8-dimethyl-2,2-dioxido-3H-3a,6-methano-2,1-benzisothiazol-1(4H)-yl]-2-buten-1-one

CAS NO.：94668-55-0

Empirical Formula: C14H21NO3S

Molecular Weight: 283.39

MDL number: MFCD00269664

PRODUCT Properties

• Melting point: 180-184 °C(lit.)
• Boiling point: 397.2±25.0 °C(Predicted)
• Density: 1.27±0.1 g/cm3(Predicted)
• pka: -14.19±0.40(Predicted)
• optical activity: [α]24/D 100°, c = 1 in ethanol

Description and Uses

(R)-(-)-(2-Butenoyl)-2,10-camphorsultam can be used:

• In the asymmetric total synthesis of lycopodine via diastereoselective cyclization and intramolecular Mannich cyclization.
• To prepare (S)-4,4-dichloro-3-methylbutanoic acid, which is utilized as a key intermediate for the total synthesis of dysideaproline E.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3