1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine , 97% , 918524-63-7

CAS NO.：918524-63-7

Empirical Formula: C16H26BN3O2

Molecular Weight: 303.21

MDL number: MFCD07437995

PRODUCT Properties

• Melting point: 125 °C
• Boiling point: 435.2±45.0 °C(Predicted)
• Density: 1.10±0.1 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• pka: 8.41±0.31(Predicted)
• form: solid
• color: white

Description and Uses

1-Methyl-4-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]piperazine is used to prepare yrazolopyridine and indazoles as histone lysine methyltransferase EZH2 inhibitors. It is also used to synthesize tetrahydropyrido pyrazines as anaplastic lymphoma kinase inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280-P305+P351+P338-P304+P340-P405-P501A
• Hazard Codes: C
• Risk Statements: 22-34
• Safety Statements: 22-26-36/37/39-45
• TSCA: No
• HS Code: 2933998090