(S)-Pyrrolidin-3-ol , 97% , 100243-39-8

Synonym(s):
(S)-3-Hydroxypyrrolidine

CAS NO.：100243-39-8

Empirical Formula: C4H9NO

Molecular Weight: 87.12

MDL number: MFCD00192426

EINECS: 600-044-6

PRODUCT Properties

• Melting point: 15°C
• Boiling point: 108-110 °C (8 mmHg)
• alpha: -6.5 º (c=3.5% in MeOH)
• Density: 1.078 g/mL at 20 °C (lit.)
• refractive index: n20/D 1.490
• Flash point: >110°C
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 14.91±0.20(Predicted)
• form: Liquid After Melting
• color: Clear light yellow to yellow
• Specific Gravity: 1.078
• optical activity: [α]20/D 6.5±1.5°, c = 3.5% in methanol
• Water Solubility: Fully miscible in water.
• Sensitive: Air Sensitive & Hygroscopic
• BRN: 4652606
• CAS DataBase Reference: 100243-39-8(CAS DataBase Reference)

Description and Uses

(S)-3-Hydroxypyrrolidine is a chiral organic compound that serves as an important building block in the synthesis of various pharmaceuticals and natural products. It is a four-membered heterocyclic amino alcohol, featuring a hydroxyl group and a stereogenic center. The 'S' prefix indicates the configuration at the stereocenter, which is crucial for its reactivity and biological activity. This compound is notable for its role as an intermediate in the synthesis of drugs, particularly those targeting the central nervous system. The enantiomeric purity of (S)-3-Hydroxypyrrolidine is often critical, as the 'R' and 'S' enantiomers can exhibit different pharmacological properties.

(S)-(-)-3-Hydroxypyrrolidine is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-40
• Safety Statements: 26-37/39-36-22
• WGK Germany: 3
• F: 10-34
• HS Code: 29339900